Deep Sequencing Shows That Oocytes Are Not Prone to Accumulate mtDNA Heteroplasmic Mutations During Ovarian Ageing
نویسندگان
چکیده
منابع مشابه
Oocyte mitochondrial deletions and heteroplasmy in a bovine model of ageing and ovarian stimulation.
STUDY HYPOTHESIS Maternal ageing and ovarian stimulation result in the accumulation of mitochondrial DNA (mtDNA) deletions and heteroplasmy in individual oocytes from a novel bovine model for human assisted reproductive technology (ART). STUDY FINDING The levels of mtDNA deletions detected in oocytes increased with ovarian ageing. Low levels of mtDNA heteroplasmy were apparent across oocytes ...
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ژورنال
عنوان ژورنال: Obstetrical & Gynecological Survey
سال: 2018
ISSN: 1533-9866,0029-7828
DOI: 10.1097/ogx.0000000000000525